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Interestingly, apoE2 and apoE3 are shown to induce proliferation of vascular endothelial cells while apoE4 decreases their proliferation [158], potentially contributing to the breakdown of the BBB
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449,450 In addition, clinical trials have shown their ability to treat cachexia in patients with gastrointestinal tumors
The effect of acute and chronic social stress on the hippocampal transcriptome in mice
doi:10.1007/s00394-021-02654-5
