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The pituitary gland, dangling from the bottom of our brain, secretes growth hormone in pulses, and this secretion is regulated by two main hormones: somatostatin blocks its release, while growth hormone-releasing hormone (or GHRH), as its name implies, encourages it

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ISBN 978-90-5702-081-0

Brewer JH, Berg D

Landmark 2017 Cell paper One of the foundational studies (by Baar et al.) was titled Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. This work demonstrated: In mice that were aged or given chemotherapy (accelerated ageing), treatment with FOXO4-DRI improved physical performance, fur quality, and renal function