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As of April 2026, no completed, peer-reviewed Phase 2 or Phase 3 human efficacy trial for BPC-157 has been published in any indication

According to one report, after E105 K unit point mutation at the NA monomer interface, the free energy of the hydrogen bond formed between Lys and Gly at residue 141 decreased from 493 kcal/mol to 481 kcal/mol

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