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doi: 10.1016/j.jare.2021.10.002 202 LinPYHuangSYSuKP

This stage requires precise temperature control (typically 0-5C), pH monitoring (6.5-7.0), and careful selection of acetylating agents to ensure site-specific modification

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Ferlay J, Shin HR, Bray F, Forman D, Mathers C, et al
Hsieh MJ, Liu HT, Wang CN, et al
