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-Glutamyltranspeptidase expression regulates the growth-inhibitory activity of the anti-tumor prodrug - L -glutaminyl-4-hydroxy-3-iodobenzene

doi: 10.1016/j.clnu.2016.12.013 125

Ferroptosis inducers that promote iron-dependent lipid peroxidation, particularly in cells with high PUFA content, are under preclinical and early clinical investigation
[DOI] [PubMed] [Google Scholar] 12.Boelaert K., Horacek J., Holder R.L., Watkinson J.C., Sheppard M.C., Franklyn J.A
Since RNAi is based on sequence homology, even short sequences of partial complementarity between the siRNA and a non-target transcript can result in unintentional silencing, potentially affecting non-target gene functions and resulting to undesirable phenotypic or ecological repercussions