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*Correspondence: Lukasz Dzialach, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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CJC-1295 comes in two forms and they behave very differently: CJC-1295 with DAC (Drug Affinity Complex) Half-life: ~8 days Dosing frequency: Once weekly Effect: Maintains a sustained, elevated GH baseline throughout the week Mechanism: The DAC modification allows CJC-1295 to bind albumin in the blood, dramatically extending its circulation time CJC-1295 without DAC (Mod GRF 1-29) Half-life: ~30 minutes Dosing frequency: Per injection (same time as Ipamorelin) Effect: Creates acute, pulsatile GH spikes more closely mimics natural GH pulsatility Mechanism: Standard peptide clearance peaks fast and clears fast Which to choose