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The phosphoinositide 3-kinase (PI3K), Akt, and mammalian target of rapamycin (mTOR) signaling pathways have been identified as significant players in mediating the effects of OS in the nervous system (Maiese et al., 2012)

The sulfhydryl-containing tripeptide glutathione (GSH), which is synthesized and maintained at high concentrations in all cells, is one of the mechanisms by which cells protect themselves from oxidative stress

Mutation Research/Reviews in Mutation Research, 787 , 108365

Figure 9 The addition of exogenous GSH or BSO had similar effect on the GSHGSSG cycle, i.e., the content of GSH increased while the GSSG content and GR activity decreased under 30 psu (100% seawater, control)

Food and Drug Administration granted approval on Monday for Opzelura, which is the first topical JAK inhibitor cream for the treatment of vitiligo for people 12 and older