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Tirzepatide is the active ingredient that is a GLP-1and GIP agonist

These patches are usually some concoction of vitamins, caffeine, or other substances, but they do not contain any actual GLP-1 medication

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You get a nice drop in blood pressure with no hypoglycemia. Pioglitazone has similarly shown a durable HbA1c reduction over 5 years and also improves insulin secretion and insulin sensitivity, reverses lipotoxicity and improves markers of nonalcoholic fatty liver disease, DeFronzo said

418,419,420 This activation holds the ability to modulate food consumption by reducing food intake and conveying signals of satiety to the brain