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Description
The starting dose is designed for tolerability, not maximum efficacy
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doi:10.1007/s001250051484
Food and Drug Administration (FDA) warned Synthetix Inc
Regulatory milestones (2017 to 2024) Clinical development advanced along two parallel formulation tracks: a subcutaneous formulation studied in the SUSTAIN and STEP programs, and an oral tablet formulation using an absorption-enhancer excipient studied in the PIONEER program
