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The substance liraglutide, under the brand name Saxenda, was introduced to the market in 2015 as the first GLP-1 RA approved as a treatment complementary to exercise and diet for weight control in patients with high BMI (obese or overweight with weight-related comorbidities) [3]

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Plaintiffs argue that Novo Nordisk and Eli Lilly failed to adequately warn patients about these risks

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CONCLUSIONS CONFLICTS OF INTEREST: No potential conflict of interest relevant to this article was reported

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46 The common mechanism of GLP-1 RA reduction in A overproduction and tau hyperphosphorylation may be the restoration of protein phosphatase 2A activity and inhibition of - and - secretase

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Immunoprecipitation was performed using an anti-HA antibody (3724S, Cell Signaling Technology

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