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The first GLP-1 injectable receptor agonist exenatide was approved by the U.S

95% CI: 1.58, 5.27

Studies are also underway for a spectrum of other conditions, including Phase 3 trials investigating non-alcoholic steatohepatitis (NASH), chronic kidney disease (CKD), and obstructive sleep apnea (OSA), as well as mid-to-late stage trials exploring potential benefits in neurodegenerative disorders like Parkinsons disease

Weight loss without exercise is possible through diet alone, but combining dietary changes with regular physical activity improves outcomes across every metric, from fat loss to muscle preservation to metabolic health