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In randomized clinical trials, tirzepatide has demonstrated mean weight reductions ranging from approximately 15% at the 5 mg maintenance dose to 20.9% at the 15 mg dose over 52 weeks [2]

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Liraglutide has anti-inflammatory effects on endothelial cells by decreasing activation of NF-kB, inhibiting TNF-alpha, and increasing nitric oxide production (28)

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