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Retatrutide has not been compared head-to-head with earlier GLP-1 medications in any clinical trials, although there is an ongoing trial called TRIUMPH-5, which is comparing it with tirzepatide

However, patients may experience minor side effects, such as injection site reactions (redness, swelling, or itching) or gastrointestinal symptoms (nausea, vomiting, or diarrhea)

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[DOI] [PubMed] [Google Scholar] 234.Ramracheya, R

For researchers running microdose protocols or titrating doses in very small increments, this level of precision is valuable