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CNVs of METTL3 were associated with OS of bladder cancer patients

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Patients with very high triglycerides require urgent medical attention: same-day assessment if triglycerides 20 mmol/L or if pancreatitis symptoms are present, and urgent specialist referral if triglycerides 10 mmol/L

Common adverse effects include: Nausea (reported by 30-40% of patients at the 2.4 mg dose) Vomiting Diarrhea Constipation Abdominal pain Decreased appetite These gastrointestinal symptoms are typically most pronounced during dose escalation and often improve with continued treatment