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When the results of the recently published outcome trials with saxagliptin [8] and alogliptin [7] were included in the analysis, the pooled incidence rates were 1.3 for DPP-4 inhibitors and 1.2 for comparators, resulting in an OR of 1.07 (95% CI 0.72, 1.58)

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For these medications to be most effective, they need to be paired with a healthy diet