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Despite this contraindication, the human relevance of GLP-1RA induced MTC in rodents has not been proven

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As established in animals, ghrelin and GLP-1 are well positioned as signaling agents within the gutbrain axis to regulate food intake and modulate motivational and reward-related behavior by increasing and decreasing reward responses, respectively

Both the Wegovy pill and shot deliver similar results in terms of weight loss, but the time it takes to see results may vary slightly due to the differences in administration