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How Orforglipron Works Like Mounjaro, Ozempic and Wegovy, orforglipron is a GLP-1 receptor agonist

Glucagon-like peptide-1 receptor agonists, but not dipeptidyl peptidase-4 inhibitors, reduce alcohol intake

Individuals with severe inflammatory bowel disease (IBD), gastroparesis (nerve damage to the gut), or a personal or family history of multiple endocrine neoplasia type 2A or 2B, medullary thyroid cancer, or pancreatitis should not take GLP-1s

doi: 10.1111/febs.16638 63 HuynhTVDavisAAUlrichJDHoltzmanDM

Dosing accuracy with compounded injectables requires careful adherence to clinician and pharmacy instructions