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When estrogen levels dip in perimenopause, ghrelin levels rise and, as a result, so do appetite, cravings for carbs, sweets, and fast food, and the accumulation of belly fat

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This decrease in TEE occurred despite an increase in lean mass and fat mass (1.7 vs 1.3 kg lean mass, P = .88 and 1.5 vs 4.6 kg fat mass, P = .04, weekly exenatide vs placebo)

You may see these medications referred to as both GLP-1 receptor agonists and GLP-1 inhibitors, which can be confusing

Evidence from nutrition and exercise research suggests protein may support muscle best when combined with regular resistance or strength training over time, not protein alone 1