tirzepatide february 2025 FDA Clarifies Compounding Rules as Supply Stabilizes February 24, 2025: PSM report

It must be refrigerated before use and can only stay outside the fridge for a limited period under strict conditions

Proper storage rules for reconstituted tirzepatide: Temperature: Refrigerate between 36 to 46 degrees Fahrenheit (2 to 8 degrees Celsius)

The most common side effects are gastrointestinal symptoms such as nausea, diarrhea, and vomiting, though some patients do report tiredness during treatment

Semaglutides action, by comparison, relies solely on GLP-1 receptors 36

For patients with severe hyperglycemia at diagnosis, tirzepatide monotherapy can achieve glycemic targets that might otherwise require combination therapy