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Description
Clinical concern regarding skeletal muscle changes during GLP-1RA therapy remains debated [40], and preclinical studies have reported context-dependent protection against muscle wasting in selected settings [42, 43]

Finally, TRANSCEND-T2D-3 (NCT06297603) will compare retatrutide to placebo over 14 months, in people with inadequately controlled T2D and moderate-or-severe renal impairment on basal insulin

Given his obesity, a GLP-1 receptor agonist can help with weight loss and lower his risk for hypoglycemia

Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease

Up to 10 sessions of cognitive behavioral therapy (CBT) focusing on motivation and craving strategies as well as relapse prevention were available to every participant over the 26 weeks