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Most physicians recommend introducing one compound before the other rather than starting both simultaneously

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The temptation is to prefill an entire vial worth of doses in one session

Increase only when the prior week felt comfortable

The most frequently reported treatment-related adverse effects occurring with GLP-1 receptor agonists are gastrointestinal, primarily nausea (occurring in 2560% of patients in clinical trials), vomiting (515%), and diarrhea (1020%) (47)
