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Given its efficacy and safety, the plecanatide 3-mg once-daily dose was approved for use by the US FDA

Most men establish sustainable routines within 2 to 3 months that outlast the medication

Data availability The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request

Phase 2 and 3 studies, such as randomized controlled trials, have shown that these agents significantly reduce liver fat content, improve liver enzyme profiles, and promote histological improvements in patients with MASLD and MASH (6, 46)

By engaging in relaxation breathing, meditation, yoga, talk therapy, or other stress-reducing activities, you can help lower cortisol which in turn helps support GLP-1 release