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The relationship between baseline adiposity, treatment-induced changes in adiposity, and subsequent MACE is unclear in GLP-1RA trials

Compare and Contrast the Glucagon-Like Peptide-1 Receptor Agonists (GLP1RAs) [PubMed] [Google Scholar] 62.Liu C., Wu T., Ren N

Serotonin also impacts intestinal metabolism, including stimulation of GLP-1 secretion by intestinal L cells (49, 50) and modulation of the local enteric and central nervous system (51)

The US Food and Drug Administration approved Zepbound to treat obesity in November

95% CI, 0.44 to 1.12
