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For diabetes management during pregnancy, insulin and other well studied options are strongly preferred

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Quite similar results, although of lesser extent and for lesser outcomes, have been observed with GLP-1RA [29]

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Some patients report feeling less energetic during the initial months of treatment, with gradual improvement as weight stabilizes and metabolic adaptation occurs

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GLP-1RAs compared to placebo In addition, the pooled results showed that first line use of GLP-1RAs has a significant predisposing effect on diarrhea (OR: 2.18, 95% CI: 1.32, 3.60

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doi:10.3390/ijms21051725 32

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