glp 1 agonist in pregnancy Maternal GLP-1 receptor activation inhibits fetal growth Continuation of GLP-1 Receptor Agonist

doi:10.1001/jama.2023.19574

For men it was exactly as expected, 7-8% less, so 20.5% and 23.2% for 9 & 12mg and about 15% for 4mg with all of them at a plateau

SUPPLEMENTAL DATA GRANTS This work was supported by NIH Grants R21HD112143 (to J.S.), R21HD111199 (to J.S.), R21HD107869 (to J.S.), DK095132 (to J.S.), and DK113007 (to J.S.)

158 DDIs with Oral Contraceptives Some GLP-1 RAs and a dual GLP-1/GIP RA altered the exposure of oral contraceptives, implying the potential for clinically significant DDIs (Table 4)

Although the reasons for the variation are still unclear, this might be due to several differences in the individual study design and patient characteristics rather than drug effect [21]