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The primary reason for discontinuation was treatment cost (37%)

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You should not use this medication if you have a known hypersensitivity to the drug or its ingredients

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But medical literature evidence suggests these same pathways may interfere with key skin functions by: Slowing fibroblast activity, reducing the production of structural proteins like collagen and elastin Decreasing cell turnover, leading to dullness and slower skin renewal Compromising the skin barrier, increasing water loss and sensitivity to environmental damage The result

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