glp-1 receptor agonists should be avoided in patients with Impact of GLP- 1 Agonist Therapy High Risk for Sarcopenia | Current Nutrition Reports GLP-1 Receptor Agonists: Mascots &
Description
Previous studies have demonstrated that the cAMP/p-AMPK/p-ACC and insulin-sensitizing pathways are pivotal to GLP-1s beneficial effects on hepatic lipid metabolism

doi: 10.1016/j.tem.2016.10.001 [DOI] [PubMed] [Google Scholar] 25

A gradual increase in drug dosage over time has been shown to reduce these side effects

13 In these early-phase studies, mazdutide exhibited a favorable safety profile, with predominantly mild-to-moderate gastrointestinal adverse effects reported

Cosmetic effects like Ozempic face (a thinner, gaunt appearance from rapid fat loss in the face) and temporary hair shedding have also been reported
