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The reduction of cardiovascular disease does not decrease medical claims to the point where it is more financially beneficial to include the GLP-1s on the drug formularies because the claims resulting from the medication alone are higher than the claims related to cardiovascular treatments

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In metabolic models, reta operates through a unique triple-hormone co-activation mechanism (GIP / GLP-1 / Glucagon), whereas tirz acts exclusively as a dual agonist targeting only the GIP and GLP-1 receptors

Weight loss of 5-10% can make a profound difference [25-28]