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These drugs were originally developed for diabetes therapy, but found uses in their ability to treat obesity and help people lose weight

Abstract The development of tirzepatide, a first in class dual glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management of type 2 diabetes and obesity

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Ethics declarations Ethics approval All patient data accessed by the researchers were fully pseudonymized

However, these medications come with serious adverse events and need closer monitoring once they are initiated