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WHO recommended that risk management plans be updated and that additional pharmacovigilance activities be implemented

However, given the variable absorption of rectal formulations among individuals, monitoring for efficacy and side effects is crucial

The key difference from CagriSema (which combines separate cagrilintide and semaglutide) is that amycretin integrates both GLP-1 and amylin agonism into a single molecule, enabling both subcutaneous and oral formulations

[DOI] [PMC free article] [PubMed] [Google Scholar] De Silva, A

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