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They're even being studied for [treating] substance abuse disorder. Who qualifies for weight-loss drugs

Regardless of cause, if left unchecked, excess weight can contribute to chronic health conditions such as arthritis and other joint issues

But these medications may also come with an increased risk for severe gastrointestinal problems, according to a new study

PMID: 41433034, PMCID: PMC12728728, DOI: 10.1001/jamacardio.2025.4824.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHospital admissionSerious adverse eventsRandomized clinical trialsEstablished CV diseaseCV diseaseSemaglutide groupRate of hospital admissionsAdverse eventsClinical trialsReduction of hospital admissionsDuration of hospital stayImpact of semaglutideBody mass indexTotal hospital admissionsEstablished cardiovascular diseaseEffect of semaglutideCV risk reductionOnce-weekly semaglutideAssociated with significant reductionsMain OutcomesMass indexPlacebo groupPatient yearsTotal hospitalHospital stay FDA Cardiovascular Indication Expansion and Dispensing of Semaglutide/Tirzepatide in CVD Patients With Overweight/Obesity Do D, Murugiah K, Sawano M, Cartwright B, Rodriguez P, Gratzl S, Curtis L, Jastreboff A , Lu Y, Stucky N

The nicotine in cigarettes can also interfere with the body's ability to absorb vitamins and minerals, leading to deficiencies that can cause muscular cramps
