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Contact your GP or prescribing clinician if you experience cold intolerance accompanied by other symptoms that might suggest thyroid dysfunction, such as: Extreme fatigue or weakness that interferes with daily activities Unexplained weight gain or cessation of weight loss despite adherence to treatment Significant hair loss or changes in hair texture Persistent constipation unresponsive to usual measures Dry, flaky skin or changes in skin texture Muscle aches, cramps, or weakness Slowed heart rate Depression or significant mood changes Cognitive difficulties, including memory problems or difficulty concentrating These symptoms could indicate hypothyroidism , which requires investigation through thyroid function tests (TSH, free T4)

Setting a reminder on your phone can prevent skipped doses
10.1016/j.molcel.2010.06.022 98

How Semaglutide and Creatine Work in Your Body Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1, a hormone regulating blood sugar and appetite

If you experience any suspected side effects from Ozempic, report them via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or the Yellow Card app)
