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Food and Drug Administration approved semaglutide for weight loss in 2021 after clinical trials showed significant, sustainable results when paired with lifestyle changes

Some people have soreness, tightness, or muscle aches around their incision for 6 months or longer

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This is caused by the combination of reduced caloric intake and stabilized blood sugar levels

Source: Rosenstock et al., The Lancet 2023 How Retatrutide Dosing Compares All three current-generation injectable weight loss drugs use once-weekly dosing with gradual titration, but the specific dose ranges and escalation timelines differ