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Impact of weight on the efficacy and safety of ustekinumab in patients with moderate to severe psoriasis: rationale for dosing recommendations

When you dose 24 hours early, you're adding new medication to an existing therapeutic level rather than restarting from zero

Disagreements between the two authors regarding study selection were resolved through discussion, or by involving a third arbitrator if consensus could not be achieved

Adjust medications Maintenance may include continuing, lowering, changing or restarting medication when clinically appropriate

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