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4 Concluding remarks, place in therapy, and future perspective Tirzepatide is a novel agent that is approved for the treatment of type 2 diabetes and will likely be approved for weight loss

Tirzepatide commonly causes fatigue , joint discomfort , and gastrointestinal effects like constipation as normal therapeutic side effects, especially during dose titration

But the most costly ones are also the most preventable
Renal function should be monitored in patients with renal impairment, particularly if experiencing severe gastrointestinal side effects leading to dehydration

A separate analysis of the SURMOUNT-1 trials first 72 weeks showed that tirzepatide led to lasting blood pressure control among 2,539 non-diabetic overweight/obese adults, leading to 6.8 mm Hg systolic and 4.2 mm Hg diastolic net reductions (mostly occurring in first 24 weeks)
