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In addition, individuals using weight-loss injections are 4.22 more at risk of developing bowel obstruction and 3.67 more likely to have gastroparesis or stomach paralysis

In the pancreas GLP-1 receptor agonism boosts insulin secretion in a glucose-dependent mannermeaning insulin rises when blood sugar is high, not indiscriminatelywhile simultaneously suppressing glucagon, the hormone that otherwise pushes the liver to release glucose

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