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Description
Individuals with a history of medullary thyroid cancer, pancreatitis, or serious gastrointestinal disorders should carefully weigh tirzepatide's risks and benefits with a provider
Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, et al
10.1016/S0140-6736(21)01330-1 [DOI] [PMC free article] [PubMed] [Google Scholar] 3
The study concluded that in patients with obesity-related heart failure and T2DM with preserved ejection fraction, semaglutide treatment resulted in significantly greater reductions in heart failure-related symptoms and physical limitations, as well as more pronounced weight loss at one year compared to placebo
Treat this as high-speculation with conservative titration
