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This can affect appetite, fullness and how quickly the stomach empties
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This activation triggers several physiological responses: it slows gastric emptying (an effect that may attenuate over time with continued use), which initially prolongs the sensation of fullness after meals

This is confirmed by the largest published phase 2 trial on retatrutide, which included 338 non-diabetic participants
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Questions to Ask Your Healthcare Provider About Tirzepatide and Breastfeeding Will tirzepatide help me more than other options while I am nursing
