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Does Semaglutide Need to Be Refrigerated?

Modern biology (INP 2.0 view) GLP-1 is secreted by intestinal L-cells and regulates insulin secretion, glucagon suppression, gastric emptying, satiety, -cell survival, gutbrain signaling, and inflammation

This narrative review synthesizes data from randomized controlled trials (RCTs) and real-world evidence (RWE) on Wegovy (semaglutide 2.4 mg, a recombinant DNA-derived GLP-1RA) in obesity with CVD, with a focus on SELECT, mediation analyses suggesting weight-independent CV effects, and outcomes in obesity-related HFpEF