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On September 16, 2025 , the FDA issued warning letters to more than 50 compounding pharmacies and telehealth companies , including Hims & Hers , for selling unapproved GLP-1s and making misleading claims

It refers to a compounded tirzepatide formulation that combines the dual GLP-1 and GIP receptor agonist (tirzepatide) with vitamin B12

A balanced intake of protein, fats, and carbohydrates supports the activity of multiple gut hormones that regulate appetite, digestion, and metabolic function

When to Adjust Your Treatment Strategy If you've been on a stable semaglutide dose for 8+ weeks and notice your appetite-suppressing effects have substantially weakenedmeaning you're eating noticeably more, hunger has returned, or weekly weight loss has stalleddiscussing a dose increase with your prescriber is reasonable and evidence-based