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Description
This includes: Stomach Pain Oily or Fatty stools Oily spotting in underwear Gas Loose stools These side effects are usually temporary and may decrease in severity the longer you take Orlistat

Oral option: Dual GIP/GLP-1 agonist: NICE recommends GLP-1 receptor agonists for type 2 diabetes (NG28) when metformin and other oral agents are insufficient, typically in patients with a BMI 30 kg/m (adjusted for ethnicity) or where weight loss would benefit other obesity-related comorbidities

The FDA label lists Type 2 diabetes and cardiovascular risk reduction in adults with Type 2 diabetes and established cardiovascular disease as approved uses
[DOI] [PubMed] [Google Scholar] 48.Pfeffer MA, Claggett B, Diaz R, Dickstein K, Gerstein HC, Kober LV, et al

The lack of a robust or consistent hemodynamic effect with GLP-1 RAs suggest that non-hemodynamic mechanisms could be responsible for the decline in albuminuria and possible eGFR preservation with these agents, including improvements in glucose control and metabolic parameters
