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Statistical analysis For each study population, the semaglutide cohort and the comparision cohort were propensity-score matched (1:1 using nearest neighbor greedy matching with a caliper of 0.25 times the standard deviation) on covariates that are potential risk factors for AUD 57,58,59,60 including demographics, adverse socioeconomic determinants of health (e.g., problems related to education and literacy, employment and unemployment, housing and economic circumstances, social environment, upbringing, primary support group including family circumstances and various psychosocial circumstances), problems with lifestyle (e.g., tobacco use, lack of physical exercise, inappropriate diet and eating habits, high-risk sexual behavior, gambling and betting, and other problems related to lifestyle including antisocial behaviors and sleep deprivation), pre-existing medical conditions, medications, medical procedures and medical visit types (outpatient, inpatient, emergency, and virtual)

The underlying reason is that, in the case of parenteral presentations, the effective doses of GLT-1 receptor agonists necessary for weight control are greater than those needed for glycemic control

The study examined nearly 500 mergers between 2002 and 2012

In certain embodiments, the article of manufacture is a pre-filled syringe

Poorly controlled diabetes during pregnancy can increase the maternal risk for diabetic ketoacidosis, preeclampsia, spontaneous abortions, preterm delivery, and delivery complications, and fetal risks for birth defects, stillbirth, excessive birth weight (macrosomia) and associated complications