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Retatrutide side effects appear to be dose-related, with higher doses generally linked to more frequent or noticeable symptoms

The authors warn that a limitation of SOUL is that the trial population was at higher cardiovascular risk than the general type 2 diabetes population, in whom around one third have established CVD and 2540% have CKD

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Diabetes type 2 and obesity are risk factors for cardiovascular disease, notably for hypertension and for heart failure (Coskun et al

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