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Stop or switch in consultation with your prescriber if any of the following appear despite hitting the 7 rules above: hand-grip strength drops more than 10% from baseline, you cannot climb one flight of stairs without significant fatigue, a 6-month DEXA shows more than 25% of total weight loss as lean mass, or you are losing more than 1.5% of bodyweight per week despite eating 1.6 g of protein per kilogram

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These efforts will be essential to advancing GLP-1based therapies for cocaine and amphetamine use disorders

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The good news is that the process is straightforward-if you meet the right health benchmarks and follow the required steps

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