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Based on rats studies, they also proposed the theory of the foregut exclusion hypothesis which suggests that delivery of nutrients to proximal small intestine leads to a release of a pro-diabetic factor, which is over secreted in diabetics [32]

For example, research has shown that excessive quantities of Erythrina abyssinica seeds are toxic and result in paralysis, unconsciousness, and even death from respiratory failure [32]

10.1111/all.14879 [DOI] [PMC free article] [PubMed] [Google Scholar] Treves N

SEMAGLUTIDE VS

It seems that FGF21 was the most efficacious, followed by resmetirom, pioglitazone, FGF19, semaglutide, and obeticholic acid (Table 2 and Fig