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You can read the abstract of this article at In the SURPASS-4 trial, the dual GIP and GLP-1 receptor agonist tirzepatide demonstrated superior reductions in HbA1c concentrations, bodyweight, and blood pressure compared to titrated daily insulin glargine in individuals with type 2 diabetes and cardiovascular risk
In clinical trials, participants reported an average weight loss of approximately 15% of their body weight over a 72-week period
Primary measures still rely on lifestyle improvements through diet and exercise
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These data emphasize the importance of monitoring UACR on treatment for prognosis
