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After analyzing all the reported suicide/self-harm cases related to GLP-1RA, it was found that 51.50% exhibited symptoms of suicidal ideation, 19.29% had attempted suicide, and 18.73% experienced intentional overdose

Central nervous system control of food intake
Diabetes Care 2016 Feb
Sources Latif W, Lambrinos KJ, Rodriguez R

Insulin is impaired in these patients