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Phase 3 programmes also evaluated long-term safety, tolerability, and metabolic outcomes, forming the basis for subsequent regulatory approvals in certain jurisdictions

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Long-term GLP-1 medication use shows cardiovascular benefits in trials, but emerging data on bone health and pancreatitis risk requires ongoing monitoring

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GLP-1(28-36)amide, a C-terminal nonapeptide of GLP-1, is a major product derived from the cleavage of GLP-1 by the neutral endopeptidase (NEP)

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Weight gain after stopping Ozempic and other GLP-1 medications is quite common

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