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Description
Low-dose radiation is regularly used for joint pain in European countries such as Germany and Spain, where it is widely accepted

Do you develop tolerance

Previously, there had only been one oral drug for this indication: metformin, which was approved in 2000

The exact approved dosing will be determined by the FDA label when orforglipron is approved

However, the regulatory pathway did not include prediabetes as an approved indication, meaning pharmaceutical companies have not submitted the evidence package needed for insurers to authorize off-label use in that earlier disease stage
