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There are two main types of heart failure, and over 50% of patients have heart failure with preserved ejection fraction (HFpEF), which is sometimes referred to as a stiff heart. With HFpEF, the heart still circulates blood normally, but the heart muscle is too stiff to relax and allow heart chambers to fill with blood between each beat

GLP-1 analogs on beta-cells: Glucose dependent insulin secretion For nearly 2 decades now, GLP-1 has been heavily investigated as the most promising therapy target in type 2 diabetes patients

Semaglutide, a GLP-1 receptor agonist originally developed for type 2 diabetes, has demonstrated an average weight loss of 15% in clinical trials when combined with lifestyle modification

The Ozempic lawsuit involves patients who allege they suffered serious gastrointestinal injuries, including gastroparesis, after using semaglutide-based drugs like Ozempic or Wegovy